Slimming pills - Weight Loss Isn't Always Easy

My doctor offered me an easy, doctor assisted weight loss plan just over a year ago. It worked some, but I never reached my goal, and I doubt I will on this program. Here is my story.

Before the slimming pills:

I like every other overweight person on the earth have been struggling with my weight for years. Lose 5 pounds, gain 10. You know the story. I personally have been told time and time again that I needed to take drastic measures. You see, all of the women in my family have died of cancer (with one remaining Aunt suffering from it now, and I too run the risk if I continue to carry around excess fat, which carries excess toxins. I even discussed gastric bypass with my husband, but decided we would ask the doctor for other options. Because I do not look morbidly obese (but the scale tells a different story), she suggested slimming pills instead.

Slimming pills prescribed by my doctor:

This last diet in particular involved the use of weight loss pills. Tenuate and Glucophage.

Tenuate is an appetite suppressant used along with diet, exercise, and behavior therapy for the short-term management of obesity. Side effects that may go away during treatment include restlessness, nervousness, difficulty sleeping, or dry mouth.

Glucophage also known as (metformin) is used as a treatment in type 2 diabetes. It improves glucose tolerance in patients and lowers plasma glucose. Glucophage is also used to treat Polycystic Ovarian Syndrome (another problem that has been plaguing me for years and is know to cause weight gain). While it also can cause a person to lose weight, a person who actually has type 2 diabetes will lose weight on this medication. The worst side effect that I have experienced is digestive problems and diarrhea.

I was originally put on these weight loss drugs and lost 40 pounds quickly and easily. The only problem with that is you need to be very overweight to use these drugs, and I, personally, had 100 pounds to lose. After taking these drugs for 6 months, my prescription was changed to phentermine alone.

Phentermine when used with diet and exercise can help you lose weight by decreasing your appetite. It can cause upset stomach, increased blood pressure, and insomnia to name a few. For me it did not work at all.

The struggle with the slimming pills begin:

After 7 months on and off Phentermine, in an effort to fool my body into thinking that it was just starting these drugs, I have gained back 10 of the 40 pounds lost, and my doctor has recently put me back on Tenuate and raised my Glucophage prescription to 2000 MG per day.

Needless to say, this stronger combination of weight loss drugs makes me feel awful and my scale is not moving.

My verdict on slimming pills:

I have concluded that there is not such thing as easy weight loss, even when the doctor promises. Of course, someone who is 30 pounds overweight can manage to get it off, but what about people who are more.

My only consolation is that I am well built, and am my weight is commonly underestimated by 30 pounds. If it weren’t so sad, it would be funny to watch the look on the doctors faces as they push the scale balance over a little at a time and say, funny, you don’t look this heavy. Oh but I am.

Now that I have finally faced the fact that I will not lose my excess weight easily, I have to resolve to lose the rest through diet (I hate that word) and exercise… the hard way.

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Israeli scientist develops new slimming drug

It's no secret that obesity statistics are on the rise, and along with them the likelihood of many more people developing heart disease and diabetes. And while the late Anna Nicole Smith helped to popularize the slimming pills in America, these pills are known for having side effects that can wreak havoc with one's health.

In response to this dilemma, Israeli researcher Dr. Nir Barak has developed what could be a weight-loss wonder drug. Working with drug company Obecure, Barak has developed a new formulation called Histalean which is based on betahistine, an approved drug marketed worldwide for the treatment of vertigo. Betahistine has been available to health authorities for over 30 years and is therefore already FDA-approved.

Histalean has been found to quell the desire to consume fatty foods, particularly in women under the age of 50. The pill works by activating chemical agents that reduce appetite. The most recent double-blind placebo-controlled study included 281patients, men and women aged 18-65, with a BMI ranging from 30 to 40. This study revealed the effects of gender and age on the pill's response.


Now, says Obecure CEO Dr. Yaffa Beck, studies of the drug will focus primarily on women under 50, since this approach seems to work best due to the presence of estrogen.


Barak is a physician in Beilinson Hospital in Petah Tikva and an instructor at Tel Aviv University's Sackler School of Medicine. While one of Barak's areas of expertise is internal medicine, he is also a US certified expert in clinical nutrition, which he practiced for two years in the University of Chicago Hospital.

"I treat people with obesity, and I also treat people who can't eat anything and rely on intravenous feedings," says Barak. "I see both ends of the spectrum."

Barak explains that Histalean is unique in comparison to other diet pills because it focuses on the histamine system, which scientists associated for years with the immune system. It's only recently that scientists began to connect the histamine system with dietary behavior, and Histalean is the only drug of its kind that has been tested safely on humans.

Barak also cautions that while he has high hopes for Histalean, there may be a long road ahead to developing an encompassing cure for obesity, because dietary behavior is more complex than it appears on the surface.

"I don't think there's one magic pill," he says. "Every individual probably has a mixture of certain mechanisms that drive them to overeat... Once we have an arsenal of four or five drugs that work on different mechanisms, then we'll be able to start managing people more efficiently when it comes to diet."

Another area that excites Barak is the possibility that Histalean can prevent weight gain in schizophrenic patients who take the anti-psychotic drug Zyprexa. This powerful medication has significant results for schizophrenia, but also causes devastating weight gain in patients, to the extent that they may sometimes gain as much as a kilo per week. Histalean activates the same appetite-reducing chemicals which are blocked by Zyprexa, leading Barak to believe that Histalean can be developed to prevent this side effect of the drug.

"The patients are gaining weight to the degree that they develop diabetes," says Barak. "This is really a very urgent problem. Schizophrenia is among the most debilitating diseases that there are-it affects every aspect of life." Coping with this debilitating illness and obesity simultaneously can be a cruel ordeal for patients, who often opt to go off their medication or switch to an older medication which causes a Parkinson's-like disease. "They would rather have Parkinson's than be obese," comments Barak.

This chance to ease the lives of people who are already under tremendous strain is attractive to Barak. "As a physician, it's very appealing for me," he says. "There's a real need here to solve an urgent medical problem-a real problem, not a cosmetic one."

www.israel21c.org

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